Careers at Children's Cancer Institute
Bioinformatics Research Assistant

Randwick - Sydney, Australia  
Employment Type:
Full-Time Fixed Term  
Computational Biology (CB)
Supporting Documentation:

  • Innovative, collaborative and positive team-orientated environment
  • Modern, world-class facilities
  • Convenient Randwick location, close to transport

Paediatric cancer takes a devastating toll on patients, their families and the community, with 950 new patients diagnosed in Australia each year. Precision cancer medicine aims to improve outcomes in cancer patients by matching patients to the optimal treatment, based on molecular tumour profiling. Bioinformatics is critical to this; however, several significant challenges remain to bridge the gap from ‘omic’ data into improved outcomes. Molecular profiling of tumours plays a critical role in the diagnosis and prognosis of patient tumours and holds enormous research potential to further understand the biological processes underling paediatric cancer.

The newly formed Computational Biology group at the Children’s Cancer Institute develops novel computational approaches to improve outcomes in patients with childhood cancer. This primarily involves the analysis of whole genome, transcriptome and methylome data, from patient tumours and preclinical models.

The main roles of this Bioinformatics Research Assistant will be (1) to support the development of cloud-based genomic analysis apps and (2) to support the analysis and delivery of data relating to each patient recruited onto the studies mentioned above, and (3), to support large-scale genomic analysis. This will involve the design, development and testing of containerised genomic apps, customised analysis workflows to achieve research outcomes based on large-scale genomic analysis. We aim to use multiple clouds to maximise our in house hybrid cloud which is in development, and commercial clouds.

Responsibilities will include, but are not limited to:

  • Support the development of cloud-based genomic applications to analyse cancer data
  • Support the development of automated systems for application testing and deployment
  • Support the development of containerised applications (e.g. docker, singularity)
  • Support the establishment of frameworks to use various commercial clouds and their batch queueing systems.
  • Potentially support the design and development of databases to store and query patient molecular data
  • Potentially support the implementation of web-based research platforms for data presentation
  • Benchmarking of novel and emerging methodologies to analyse patient molecular data
  • Support the research and grant administrative activities of the Computational Biology group
  • Other duties as assigned

Qualifications, experience and skills required:

  • Master’s in bioinformatics, software engineering, computer science, physics, or related degrees
  • Strong expertise in at least one of these areas:
    • Bioinformatics
    • Software engineering
    • Computer science
    • Programming
  • Expertise in at least two of bash, R, perl or python is essential
  • Highly motivated, creative and empathetic is essential
  • Experience working with a team is highly desired
  • Expertise in at least one of genetics, genomics, next generation sequencing, cancer biology or molecular is desirable, but not essential
  • Expertise in cloud-based and/or high-performance computing platforms and software containers is highly desirable, but not essential
  • Expertise in whole genome sequencing and RNA sequencing data analysis is desirable, but not essential

We are strongly committed to the growth of our employees so all staff can fulfil their aspirations. You'll be rewarded with a friendly and professional flexible work environment, comprehensive on-campus facilities, competitive salary, salary packaging options, access to a leading EAP program and regular social activities. Join a group of dedicated people in a performance-driven environment to achieve success and discover what it's like to look forward to coming to work every day and make a real difference. We're looking for people who share our values of accountability, integrity and camaraderie, teamwork, sharing and excellence, success and satisfaction.

A detailed job description and additional information about Children's Cancer Institute can be found on our website at: We embrace diversity and encourage applications from people from diverse backgrounds and cultures.

To apply, please click the 'APPLY' link and forward both your resume AND cover letter clearly addressing the qualifications, experience and skills required. Note: Applications will be reviewed prior to the closing date; which is dependent on the status of the recruitment process.