Careers at Children's Cancer Institute
Bioinformatician

Location:
Children's Cancer Institute  
Employment Type:
Full-Time Fixed Term  
Department:
Metal-Targeted Therapy & Immunology
Salary:
$80k + Super + Salary Packaging Benefits

What’s in it for you?

  • Work with purpose – help us find a cure for childhood cancer
  • Access to our ‘FlexBEST’ program – true flexibility from day 1 - options include hybrid working, school-friendly hours, and 9-day working fortnight
  • Focus on employee wellbeing, including a leading EAP program, and up to 5 gifted wellbeing days off (paid) per year
  • Investment in leadership development and career advancement opportunities
  • 13 weeks paid parental leave on top of any government funded paid parental leave
  • Convenient Randwick location, across the road from UNSW Light Rail stop
  • THRIVE – Wellbeing initiatives to support “life balance”
  • REDI – Respect, Equity, Diversity, and Inclusion initiatives
  • Social Committee – Fun, engaging events to foster connection
  • Personal Best – Structured Individual and Team goal setting to achieve Personal & Career development

 

Every year in Australia there are around 950 new children diagnosed with cancer. To improve the outcomes of children with cancer, the Children’s Cancer Institute (CCI) is looking for a highly motivated bioinformatician to study the effect of novel therapeutics targeting epigenetic aberrations in brain cancer.

The Metal-Targeted Therapy and Immunology (MTTI) group focus its research on the childhood cancers neuroblastoma and high-grade gliomas. This team is investigating the role of metals, such as copper, in the growth of these tumours with the aim to develop drugs that specifically target cellular pathways involving these metals, thereby halting tumour progression. The Bioinformatics group at CCI plays a crucial role in unravelling and understanding the molecular basis, tumour microenvironment and the drivers of a child’s tumour. The team is essential for the development of pipelines to dissect key biological drivers through the integrative analysis and interpretation of ‘big-data.’

Currently, we are looking for a strong and creative programmer with an eye for detail and a passion for biological research to

  • Conduct research either as a member of a team or independently
  • Support related research projects within the MTTI group
  • Perform benchmarking analysis of software and develop/optimise pipelines for research analysis
  • Produce, or contribute to high quality publications
  • Contribute to research funding submissions
  • Present research data at conferences and seminars
  • Contribute to the bioinformatics education of other researchers

The bioinformatician will be embedded within the Metal Targeted Therapy and Immunology research group, while strongly interacting with and being fully supported by the Bioinformatics group. This unique position not only offers the opportunity for the candidate to develop new analysis approaches and make new informatic discoveries, but also to create their own research questions to explore independently.

 

Responsibilities will include, but are not limited to:

  • Generate reproducible, high quality research results
  • Demonstrated ability to design and conduct experiments independently as well as in a team environment
  • Demonstrated experience in interpreting and analysing molecular biology data
  • Develop and implement algorithms using omics data (ie. RNA-seq, scRNA-seq, spatial transcriptomics and ChIP-seq)
  • Support spin-off research projects resulting from the MTTI program
  • Support research projects and grant administrative activities of the MTTI group
  • Statistical analysis for clinical and bench-side research
  • Assess, understand and implement bioinformatics tools and generate bioinformatics pipelines
  • Teach, assist and mentor scientists in the field of bioinformatics
  • Any other tasks required by the team leader or delegated senior team members

 

Qualifications, experience, and skills required:

Qualifications

  • Minimum BSc in either Bioinformatics, Biology, Molecular Biology, Computer Science or Statistics

Experience and requirements

  • Strong expertise in at least one of the following areas:
    • Bioinformatics
    • Computer Science
    • Programming
  • Expertise in at least two of bash, R, python, or perl is essential
  • Expertise in at least one of the following areas is desirable:
    • Immunotherapy
    • Immunogenomics
    • Next generation sequencing
    • Cancer-, cell- or molecular biology
  • Expertise in the interpretation of spatial transcriptomics is desirable, but not essential
  • Highly motivated, creative and empathetic is essential
  • Strong abilities in problem-solving and independent thinking

 

Join a group of dedicated people in a performance-driven environment to achieve success and discover what it's like to look forward to coming to work every day and make a real difference.

A detailed job description and additional information about Children's Cancer Institute can be found on our website at: https://www.ccia.org.au/careers-study . We embrace diversity and encourage applications from people from diverse backgrounds and cultures.

To apply, please click the 'APPLY' link and forward both your resume AND cover letter (mandatory) clearly addressing the qualifications, experience and skills required.

Note: Applications will be reviewed prior to the closing date; which is dependent on the status of the recruitment process. Only successfully shortlisted candidates will be contacted.