Careers at Children's Cancer Institute
Senior Scientist

Randwick - Sydney, Australia  
Employment Type:
Full-Time Fixed Term  
Personalised Medicine (PM)
Supporting Documentation:

  • Innovative, collaborative and positive team-orientated environment
  • Modern, world-class facilities
  • Convenient Randwick location, close to transport

Children’s Cancer Institute is the only medical research institute in Australia wholly dedicated to curing childhood cancer and one of the leading medical childhood cancer research institutes worldwide. Our vision is to save the lives of all children with cancer and improve their long-term health, we don’t just hope to do it, we will do it; and we’re looking for the brightest minds to help us get there. Children’s Cancer Institute provides the best possible environment for our staff thrive with state-of-the-art facilities at the Lowy Cancer Research Centre, UNSW Australia – one of the leading cancer research centres in the world.

We are leading the national Zero Childhood Cancer personalised medicine program for children with the most aggressive cancers, in partnership with the Sydney Children’s Hospitals Network. Zero Childhood Cancer is the most exciting childhood cancer research initiative ever undertaken in Australia and is a world-leading initiative

We currently have an outstanding opportunity for a motivated post doctoral researcher with drive and exceptional initiative to provide significant input to and participate in studying the biology of genomic discoveries arising from the Zero Childhood Cancer National Clinical Trial by developing model systems to investigate the functional molecular consequences of mutations/fusions, developing functional genomic screens, test drug responses, and identifying potential drug targeting strategies to translate to the clinic. Additionally, the successful candidate will leverage their strong initiative and experience in the biology and genomics of paediatric sarcoma building on their existing experience with phosphoproteomics / kinomics to study novel and actionable targets. You will join our Personalised Medicine team on a full-time fixed-term three (3) year contract with great potential for extension.

Responsibilities will include, but are not limited to:
  • Undertake cellular and molecular studies in models of high-risk childhood cancers to understand the molecular mechanisms driving cancer development and progression.
  • Provide significant input into research directions and develop an independent program of paediatric sarcoma research. This independent research will be aimed at finding novel targets and accompanying targeted treatments in paediatric tumours
  • Conduct research both as a team member and independently to undertake drug screening in models of paediatric sarcoma and other high risk paediatric cancers for the purposes of identifying potentially active drugs in individual tumours, and to provide basic research into the associations between genomic changes in sarcomas and drug responses.

  • Qualifications, experience and skills required:
    • At least 5 years postdoctoral research experience
    • Demonstrated ability to design and conduct experiments independently as well as in a team environment
    • The candidate will have had experience in studying the biology of paediatric sarcoma, and experience in the development of in vivo and in vitro models of paediatric sarcoma. This will include an interest in (but not restricted to) Ewing sarcomas, osteosarcomas, rhabdomyosarcoma and synovial sarcomas
    • The candidate will have published experience in the integration of high-throughput genomics/proteomics/kinomics data with validation studies in vitro, in vivo and on patient material. Using such data as a methodology to study novel and actionable targets in sarcomas will be a significant advantage
    • The successful candidate will have established and maintained strong networks in the field of paediatric sarcoma research, and a broad-based international research experience will be considered an advantage.


    Children’s Cancer Institute is strongly committed to the growth of their employees, so all team members can fulfil their aspirations. You'll be rewarded with a friendly and professional flexible work environment, comprehensive on-campus facilities, competitive salary, salary packaging options, on-site parking options, access to a leading EAP program and regular social activities. Join a group of dedicated people in a performance-driven environment to achieve success and discover what it's like to look forward to coming to work every day and make a real difference. We're looking for people who share our values of accountability, integrity and camaraderie, teamwork, sharing and excellence, success and satisfaction.

    A detailed job description and additional information about Children's Cancer Institute can be found on our website at: We embrace diversity and encourage applications from people from diverse backgrounds and cultures.

    To apply, please click the 'APPLY' link and forward both your resume AND cover letter clearly addressing the qualifications, experience and skills required.  Note: Applications will be reviewed prior to the closing date; which is dependent on the status of the recruitment process.