Careers at Children's Cancer Institute
Research Assistant - Personalised Medicine

Randwick - Sydney, Australia  
Employment Type:
Full-Time Fixed Term  
Personalised Medicine (PM)
$63-65k + Super + Salary Packaging Benefits
Supporting Documentation:

  • Innovative, collaborative and positive team-orientated environment
  • Modern, world-class research facilities
  • Convenient Randwick location, close to transport
  • Flexible working options

The ZERO Childhood Cancer National Personalised Medicine Program (ZERO) is Australia’s first and most comprehensive personalised medicine program for children and adolescents with very high-risk cancer (anticipated likelihood of survival <30%). A unique, multidisciplinary program bringing together cutting-edge science, the latest technology, and the brightest minds in research and clinical care, it is on a path to change the model of care for children with cancer today. Having already demonstrated significant impact in improving the lives of children faced with the most challenging prognosis, the program is now in preparation to expand and grow to include all children with cancer by 2023.

This role is a key support position for senior post-doctoral scientists undertaking work within ZERO Preclinical Drug Testing Core. The Research Assistant will be responsible for the development, expansion and validation of in vitro cultures and patient-derived xenografts (PDXs), critical for supporting the in vitro drug screening and in vivo drug efficacy pipelines- both central components within ZERO. The Program strives to deliver rapid results using primary patient samples. This position requires excellent teamwork and communication skills, adaptability, meticulous attention to detail, and close adherence to deadlines so that test results can be provided in a timely manner.


Responsibilities will include, but are not limited to:

  • To develop and maintain primary cultures from personalised medicine patient samples
  • Assist in the validation of cell cultures and preparation of cells for in vitro drug screening
  • Assist Research Officers in the research and development of novel primary cell culture techniques
  • To establish and maintain patient derived xenograft models
  • To design and conduct experiments as part of a team to test the efficacy of novel drugs against patient derived xenograft models of liquid (haematological cancers) and solid tumours including neuroblastomas, sarcomas, and CNS tumours.
  • Ability to work with clinical patient samples to track and meticulously record all aspects of laboratory operations whilst ensuring patient confidentiality.
  • Collating, organising and presenting experimental results and assistance with preparing scientific reports

Qualifications, experience and skills required:

  • Minimum BSC in a relevant scientific or medical field
  • 2+ years relevant laboratory experience highly desirable
  • Experience with cancer cell biology highly desirable
  • Experience with general procedures involving establishment of xenograft models and in vivo experiments (handling, monitoring and treatments) highly desirable
  • Experience with primary in vitro cell cultures highly desirable
  • Experience with PC2 and WHS standards and behaviour highly desirable
  • Demonstrated ability to design and conduct experiments independently as well as in a team environment
  • Exhibits a high degree of professionalism and respect for others
  • Advanced computer skills

This is an excellent opportunity to work in an inspiring workplace. You'll be rewarded with a friendly and professional flexible work environment, comprehensive on-campus facilities, competitive salary, salary packaging options, access to a leading EAP program and regular social activities. Join a group of dedicated people in a performance-driven environment to achieve success and discover what it's like to look forward to coming to work every day and make a real difference.

A detailed job description and additional information about Children's Cancer Institute can be found on our website at: . We embrace diversity and encourage applications from people from diverse backgrounds and cultures.

To apply, please click the 'APPLY' link and forward both your resume AND cover letter (mandatory) clearly addressing the qualifications, experience and skills required.

Note: Applications will be reviewed prior to the closing date; which is dependent on the status of the recruitment process. Only successfully shortlisted candidates will be contacted.